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Amy forces Raj to leave, so he crashes on Leonard and Penny's date.
Leonard, unlike Penny, wants to discuss their relationship and resents Raj's intrusion, but has to accommodate him for Penny.
The actors were required to act out "motions of microgravity" in order to create "theatrical authenticity".
Howard's mother, furious to learn he plans to leave her for Bernadette, calls him at the ISS.
Amy and Penny later see Alex flirting with Leonard in the Caltech cafeteria, now making Penny jealous.
Amy points out that though Penny is unsure of her feelings for Leonard, subconsciously the thought of him with another woman bothers her. After finding an elementary school project of Sheldon's with Nobel potential, Alex visits him at home, again flirting with Leonard, whereupon Penny drags him to her apartment for sex.
The season finale of season 5 depicted Howard Wolowitz traveling to the International Space Station (ISS) on board a Soyuz rocket, and season 6 features him working in the ISS.
which along with NCIS, made CBS the first network to have two scripted series reach that large an audience in the same week since 2007.
This success has been attributed to the sitcom's exposure in syndication, its late 2010 move to a new time-slot, and the influence of showrunner Steven Molaro (who took over from Bill Prady) on the characters' storylines.
During the season, Kevin Sussman became a part of the main cast as Stuart Bloom.
Mark Cendrowski was nominated for the Directors Guild of America Award for Outstanding Directing – Comedy Series for the season premiere "The Date Night Variable".